Triethylamine → HCID 19096808, compound

HRID 893242Notes

Reaction equation

HRID 893242 reaction equation
[Br:1][C:2]1[CH:8]=[CH:7][C:5]([NH2:6])=[C:4]([CH3:9])[CH:3]=1.Cl[C:11]([C:13]1([C:20]([O:22][CH3:23])=[O:21])[C:15]([CH3:17])([CH3:16])[C:14]1([CH3:19])[CH3:18])=[O:12].C(N(CC)CC)C>C1C=CC=CC=1>[Br:1][C:2]1[CH:8]=[CH:7][C:5]([NH:6][C:11]([C:13]2([C:20]([O:22][CH3:23])=[O:21])[C:14]([CH3:18])([CH3:19])[C:15]2([CH3:16])[CH3:17])=[O:12])=[C:4]([CH3:9])[CH:3]=1

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 114234-Bromo-2-methylanilineHCID 19096856HCID 19096856, compound

Product 1

HCID 19096808HCID 19096808, compoundYield 60%

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

4-Bromo-2-methylaniline (2.09 grams, 0.01 mole) and methyl 1-chlorocarbonyl-2,2,3,3-tetramethylcyclopropanecarboxylate (2.45 grams, 0.01 mole), prepared in Part B, were reacted in the presence of 1.13 grams (0.01 mole) of triethylamine in 70 milliliters of benzene solution in a manner similar to that described in Example I to give 2.13 grams (0.006 mole) of methyl 1-(4-bromo-2-methylphenylamino-carbonyl)-2,2,3,3-tetramethylcyclopropaneca rboxylate.

Sources & evidence

ORD record
ord-e51e580f7f74466393d6cca84f5ff4a2
Source dataset
uspto-grants-1992_06
Patent number
US05123951

Reaction notes

Loading…