Sodium Iodide → HCID 15702895, compound

HRID 893267Notes

Reaction equation

HRID 893267 reaction equation
Cl[CH2:2][CH2:3][CH2:4][C:5]1[CH:13]=[CH:12][C:8]([CH2:9][C:10]#[N:11])=[CH:7][CH:6]=1.[I-].[Na+].[CH3:16][CH:17]1[CH2:22][CH:21]([CH3:23])[CH2:20][NH:19][CH2:18]1>CC(C)=O>[CH3:16][CH:17]1[CH2:22][CH:21]([CH3:23])[CH2:20][N:19]([CH2:2][CH2:3][CH2:4][C:5]2[CH:13]=[CH:12][C:8]([CH2:9][C:10]#[N:11])=[CH:7][CH:6]=2)[CH2:18]1

Participants

5

Reactant 3

HCID 5238Sodium IodideHCID 1182593,5-DimethylpiperidineHCID 15702884HCID 15702884, compound

Product 1

HCID 15702895HCID 15702895, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

In a 250 ml round bottom flask 5.3 g of 4-(3-chloropropyl)benzylcyanide, 4.4 g of sodium iodide, 62.2 g of 3,5-dimethylpiperidine and 32.9 ml of acetone are mixed together and boiled for 1 hour at reflux.

Workup

  1. temperatureat reflux

Sources & evidence

ORD record
ord-c43cbaa25bfd40a294eff51bf8bd5b26
Source dataset
uspto-grants-1992_06
Patent number
US05124326

Reaction notes

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