Methyl iodide → HCID 19891954, compound

Participants

Reaction Steps

In benzene (10 ml) was dissolved by heating (1-methyl-2-piperidyl)methyl 1H-indole-3-carboxylate (0.10 g, 0.37 mmol) followed by addition of a benzene (5 ml) solution of methyl iodide (0.14 g, 0.99 mmol). The mixture was allowed to react in a stainless steel sealed tube at 100° C. for 2 hours. The reaction tube was cooled, and a reaction product was scraped out by a spatula, washed with IPE and dried (70° C.) under reduced pressure to give 0.11 g of the title compound as a yellow foamy solid. m.p. 95°-97° C.;

Provenance & Evidence