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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 893336Generated: October 25, 2026

Pyridine-2-carbonitrile → 4-(4-Hydroxy-5-phenyl-2-thiazolyl)benzoic acid

https://huagongshe.com/reaction/893336

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPyridine-2-carbonitrileHCID 7522—
Reactant4-Cyanobenzoic acidHCID 12087—
ReactantHCID 178473673HCID 178473673—
Reactant2-hydroxy-2-phenylethanethioic S-acidHCID 178526203—
Product4-(4-Hydroxy-5-phenyl-2-thiazolyl)benzoic acidHCID 15691817—

Reaction Steps

The title compound was prepared according to the method of Scheme I in a manner analogous to Example 1 except thiomandelic acid and 4-cyanobenzoic acid were used instead of thiolactic acid and 2-cyanopyridine respectively.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05124342
Source datasetuspto-grants-1992_06
ORD IDord-51c392074874456cad957fd0ff50ce44
Source noteuspto-grants-1992_06