反应详情

41 g of methyl 4-[4-(4-methoxybenzoyl)phenoxy]butyrate from Example 2 are dissolved in 600 ml of dimethoxyethane/water 4:1, and 63 ml of 2N sodium hydroxide solution are added. The mixture is stirred at room temperature for 4 hours, then acidified to pH 3 with 3N hydrochloric acid, and the organic solvent is removed in vacuo. The acid which has separated out is filtered off and dried over phosphorus pentoxide in vacuo.

1. additionare added
2. customthe organic solvent is removed in vacuo
3. customThe acid which has separated out
4. filtrationis filtered off
5. dry with materialdried over phosphorus pentoxide in vacuo