Lithium Hydroxide → HCID 15341824, compound

Participants

Reaction Steps

The compound of Example 45 (70 mg, 0.1395 mmol) and 279 μl of 1 M lithium hydroxide was added to 2.0 ml of methanol, and the reaction mixture was stirred at room temperature overnight. The solvent was removed under vacuum and 2.0 ml of water was added, and the solution was acidified with 10% hydrochloric acid and then extracted three times with ethyl acetate. The extracts were combined and the solvent was removed under vacuum to give the product.

Provenance & Evidence