Hydrochloric Acid → HCID 15341831, compound

Participants

Reaction Steps

The compound of Example 52 (95 mg, 0.19 mmol) and 380 μl (0.38 mmol) of 1 M lithium hydroxide were added to 2.0 ml of methanol, and the reaction mixture was stirred for four hours at room temperature. The solvent was removed under vacuum to give a white solid which was suspended in 5.0 ml of water. The mixture was acidified with 10% hydrochloric acid, stirred and filtered to remove the resultant solid which was then dried at 40° C. overnight in a vacuum oven to give the product.

Provenance & Evidence