Lithium Hydroxide → HCID 15341834, compound

Participants

Reaction Steps

The compound of Example 55 (100 mg, 0.195 mmol) and 390 μl of 1 M lithium hydroxide (0.3896 mmol) were added to 2.0 ml of methanol, and the reaction mixture was stirred at room temperature for 4 hours. The solvent was removed under vacuum, 5.0 ml of water was added to the residue, and the mixture was acidified with 10% hydrochloric acid. The mixture was filtered, and the white solid which was recovered was dried in a 40° C. oven overnight to give the product.

Provenance & Evidence