Pyridine → HCID 12266211, compound

HRID 893556Notes

Reaction equation

HRID 893556 reaction equation
[Cl:1][CH2:2][C:3]([C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1)=[O:4].[N:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1>C(#N)C>[Cl-:1].[CH2:2]([N+:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)[C:3]([C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1)=[O:4]

Participants

4

Reactant 2

HCID 1049Pyridine2×HCID 107572-Chloroacetophenone

Product 1

HCID 12266211HCID 12266211, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Conditions

Temperature
70 °C

Procedure

Phenacylpyridinium chloride was prepared by reacting 424 grams chloroacetophenone with 322 ml pyridine by dropwise adding the pyridine to the former in 1400 ml acetonitrile at 65° C. A crystalline mass was obtained which was heated to 70° C. and allowed to cool to 10° C., then filtered and washed with 500 ml acetonitrile. The dried product (626.5g) had a melting point of 203-206° C.

Workup

  1. customA crystalline mass was obtained which
  2. temperatureto cool to 10° C.
  3. filtrationfiltered
  4. washwashed with 500 ml acetonitrile

Sources & evidence

ORD record
ord-ece249515f6942958d0801be21b7a199
Source dataset
uspto-grants-1992_06
Patent number
US05126233

Reaction notes

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