HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 1-Cyclobutyl-3-methyl-1H-pyrazole-5-carbonyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 129506-38-3 | HCID 15136779 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | 1-Cyclobutyl-3-methyl-1H-pyrazole-5-carbonyl chloride | HCID 15136781 | 96.1% |
Reaction Steps
To 3.02 g of 1-cyclobutyl-3-methyl-1H-pyrazole-5-carboxylic acid were added 60 ml of benzene and 10 ml of thionyl chloride. The mixture was refluxed for two hours. Then the solvent was distilled off under reduced pressure and thus 3.2 g of 1-cyclobutyl-3-methyl-1H-pyrazole-5-carboxylic acid chloride was obtained (yield: 96.1%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05126362 |
| Source dataset | uspto-grants-1992_06 |
| ORD ID | ord-ffadd85cf4ba485aa0e18c812058bc48 |
| Source note | uspto-grants-1992_06 |