Phthaloyl chloride → HCID 54228578, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 8.0 g of (S)-(-)-2-fluoro-2-(trifluoromethyl)hexanoic acid and 24.0 g of phthalyl chloride was stirred at 80° C. for 24 hours. Subsequently, the reaction mixture was distilled under reduced pressure, thereby obtaining 8.2 g of (R)-(-)-2-fluoro-2-(trifluoromethyl)hexanoyl chloride having the physical properties as mentioned hereinbefore.

Provenance & Evidence