HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → HCID 12800082, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 4-(Chloromethyl)-2-methyl-1,3-thiazole | HCID 736341 | — |
| Reactant | HCID 12800072 | HCID 12800072 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 12800082 | HCID 12800082 | 20.8% |
Reaction Steps
The product of Example 2 (5.04 g), 2-methyl-4-chloromethyl-1,3-thiazole (4 g) and sodium hydride (1.56 g) in 120 ml dry DMF were treated at 0° C. according to the procedure of Example 3. Work-up yielded 1.67 g of title product (chromatographed on silica gel and by h.p.l.c.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04282028 |
| Source dataset | uspto-grants-1981_08 |
| ORD ID | ord-a8ecc7cdfe9a46789dcbf9ea5bef30b6 |
| Source note | uspto-grants-1981_08 |