Hydrochloric Acid → HCID 178470423, compound

HRID 894114Notes

Reaction equation

HRID 894114 reaction equation
[CH3:1][C:2]1[C:6]([N+:7]([O-:9])=[O:8])=[C:5]([C:10]([OH:12])=[O:11])[NH:4][N:3]=1.Cl.S(=O)(=O)(O)O.[CH2:19](O)[CH3:20]>>[CH3:1][C:2]1[C:6]([N+:7]([O-:9])=[O:8])=[C:5]([C:10]([O:12][CH2:19][CH3:20])=[O:11])[NH:4][N:3]=1

Participants

5

Reactant 4

HCID 313Hydrochloric Acid2×HCID 702EthanolHCID 1118Sulfuric AcidHCID 178434627HCID 178434627, compound

Product 1

HCID 178470423HCID 178470423, compoundYield 94%

Procedure

A solution of 3-methyl-4-nitropyrazole-5-carboxylic acid (70.4 g, 0.41 mol) in ethanol (300 ml) was saturated with hydrogen chloride prepared from the combination of concentrated hydrochloric acid (430 ml) and concentrated sulphuric acid (430 ml) at 0°. After standing overnight at room temperature, the reaction mixture was evaporated to dryness yielding 77.1 g (94%) of an oil which crystallized after seeding, m.p. 81°-86°.

Workup

  1. customthe reaction mixture was evaporated to dryness

Sources & evidence

ORD record
ord-ad063cf3a5954f3cb339d98949df91af
Source dataset
uspto-grants-1981_08
Patent number
US04282361

Reaction notes

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