Hydrochloric Acid → HCID 12224259, compound

HRID 894158Notes

Reaction equation

HRID 894158 reaction equation
[CH2:1]([CH:5]([CH:9]1[O:11][CH2:10]1)[C:6](=O)[CH3:7])[CH2:2][CH2:3][CH3:4].Cl>C(Cl)(Cl)Cl>[CH3:10][C:9]1[O:11][CH:7]=[CH:6][C:5]=1[CH2:1][CH2:2][CH2:3][CH3:4]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 21162776HCID 21162776, compound

Product 1

HCID 12224259HCID 12224259, compoundYield 35%

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

15.6 Grams of 3-butyl-4,5-epoxy-pentan-2-one was added to chloroform (300 ml), and then conc. hydrochloric acid (3 ml) was added thereto, followed by refluxing for 10 hours. The chloroform layer was washed with water and then with an aqueous sodium hydrogen carbonate solution, followed by concentrating. The residue was column chromatographed on silica gel to obtain 4.8 g of 2-methyl-3-butylfuran.

Workup

  1. temperatureby refluxing for 10 hours
  2. washThe chloroform layer was washed with water
  3. concentrationby concentrating
  4. customchromatographed on silica gel

Sources & evidence

ORD record
ord-497e32bf961545b8b5b5526a1591d226
Source dataset
uspto-grants-1981_08
Patent number
US04282372

Reaction notes

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