HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → HCID 178514903, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Ammonium Chloride | HCID 25517 | — |
| Reactant | Sodium Azide | HCID 33557 | — |
| Reactant | 9-Cyano-6,11-dihydro-11-oxodibenz[b,e]oxepin | HCID 12929140 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Sodium Carbonate | HCID 10340 | — |
| Product | HCID 178514903 | HCID 178514903 | — |
Reaction Steps
Heat a mixture of 800 mg. of the nitrile of Example 2, Step F, 293 mg. of sodium azide and 265 mg. of ammonium chloride in 25 ml. of dimethylformamide at 130°-135° C. for 6 hours. Dilute the mixture with water and excess sodium carbonate. Extract with ethyl acetate. Acidify the aqueous phase and separate and precipitate by filtration to obtain the title product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04282365 |
| Source dataset | uspto-grants-1981_08 |
| ORD ID | ord-dcbf31fad5c046beac63d224d1423e91 |
| Source note | uspto-grants-1981_08 |