反应详情

Reflux 1.0 gm of 2-chlorocarbonyl-6,11-dihydro-11-oxodibenz[b,e]oxepin in 20 cc of ethyl acetate containing 2.0 gm of glycine for 5 hours. Evaporate the mixture to dryness. Add 30 cc of water to the solid residue and stir at room temperature for one hour. Separate the solid by filtration and recrystallize from ethanol to obtain the title product.

1. customEvaporate the mixture to dryness
2. additionAdd 30 cc of water to the solid residue
3. customSeparate the solid
4. filtrationby filtration
5. customrecrystallize from ethanol