2-Thiocresol → HCID 12963243, compound

HRID 894260Notes

Reaction equation

HRID 894260 reaction equation
[Cl:1]N1C(=O)CCC1=O.[C:9]1([CH3:16])[C:10]([SH:15])=[CH:11][CH:12]=[CH:13][CH:14]=1>C1C=CC=CC=1>[C:9]1([CH3:16])[C:10]([S:15][Cl:1])=[CH:11][CH:12]=[CH:13][CH:14]=1

Participants

4

Reactant 2

HCID 87122-ThiocresolHCID 31398Chlorosuccinimide

Product 1

HCID 12963243HCID 12963243, compoundYield 87.1%

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent2×

Procedure

N-chlorosuccinimide (5.34 g., 40 mmoles) was slurried in 50 ml. of benzene and cooled in an ice-water bath. o-Toluenethiol (4.96 g., 40 mmoles) in 50 ml. of benzene was added dropwise over 15 minutes. The reaction was warmed to room temperature and stirred for approximately 16 hours. The reaction mixture was filtered and o-toluenesulfenyl chloride (5.53 g.) obtained as an oil by evaporation in vacuo.

Workup

  1. filtrationThe reaction mixture was filtered

Sources & evidence

ORD record
ord-8995f96c7ccc4643b2d0dde95f170065
Source dataset
uspto-grants-1981_08
Patent number
US04282246

Reaction notes

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