Ethanol → HCID 12918697, compound

HRID 894303Notes

Reaction equation

HRID 894303 reaction equation
[CH3:1][C:2]1[CH:7]=[C:6]([CH3:8])[CH:5]=[CH:4][C:3]=1[CH2:9][C:10](=[O:18])[CH2:11][CH2:12][C:13]([O:15]CC)=O.[Na].C(O)C>C1(C)C=CC=CC=1>[CH3:1][C:2]1[CH:7]=[C:6]([CH3:8])[CH:5]=[CH:4][C:3]=1[CH:9]1[C:10](=[O:18])[CH2:11][CH2:12][C:13]1=[O:15]

Participants

5

Reactant 3

HCID 702EthanolHCID 5360545SodiumHCID 12918692HCID 12918692, compound

Product 1

HCID 12918697HCID 12918697, compoundYield 49.2%

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

Utilizing 21.46 g. (0.0864 mol) of ethyl 5-(2',4'-dimethylphenyl)-4-ketopentanoate, 4.00 g. (0.173 mol) of sodium, 125 ml of dry ethanol, 200 ml of toluene, and the procedure described in Example I, Part D, 8.60 g (49% yield) of 2-(2',4'-dimethylphenyl)-1,3-cyclopentanedione was obtained as a white, crystalline solid, m.p. 198.0°-200.5° C.

Sources & evidence

ORD record
ord-d540e2c22c5f4f63a709b62028e1eb5d
Source dataset
uspto-grants-1981_08
Patent number
US04283348

Reaction notes

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