Ethyl bromoacetate → HCID 20519243, compound

HRID 894307Notes

Reaction equation

HRID 894307 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][N:5]=[CH:4][CH:3]=1.[Br:8][CH2:9][C:10]([O:12][CH2:13][CH3:14])=[O:11]>>[Br-:8].[C:10]([CH2:9][N+:5]1[CH:6]=[CH:7][C:2]([Cl:1])=[CH:3][CH:4]=1)([O:12][CH2:13][CH3:14])=[O:11]

Participants

3

Reactant 2

HCID 7748Ethyl bromoacetateHCID 122884-Chloropyridine

Product 1

HCID 20519243HCID 20519243, compound

Procedure

A solution of 1.1 g. (10 mmoles; 0.95 ml.) of 4-chloropyridine in 10 g. (60 mmoles) of ethyl bromoacetate is kept at 5° for 48 hours. The mixture is diluted with 15 ml. of ether, filtered and the solid is washed well with ether.

Workup

  1. additionThe mixture is diluted with 15 ml
  2. filtrationof ether, filtered
  3. washthe solid is washed well with ether

Sources & evidence

ORD record
ord-d9fc9b809a6142f19b7ddc61c07db719
Source dataset
uspto-grants-1981_08
Patent number
US04283397

Reaction notes

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