Hydrazine → HCID 12889662, compound

HRID 894325Notes

Reaction equation

HRID 894325 reaction equation
[N:1]([CH2:4][CH:5]1[O:9][N:8]=[C:7]([C:10]2[CH:15]=[CH:14][C:13]([Cl:16])=[CH:12][CH:11]=2)[CH2:6]1)=[C:2]=[S:3].[NH2:17][NH2:18]>C(O)C>[Cl:16][C:13]1[CH:12]=[CH:11][C:10]([C:7]2[CH2:6][CH:5]([CH2:4][NH:1][C:2](=[S:3])[NH:17][NH2:18])[O:9][N:8]=2)=[CH:15][CH:14]=1

Participants

4

Reactant 2

HCID 9321HydrazineHCID 12889638HCID 12889638, compound

Product 1

HCID 12889662HCID 12889662, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A 25 g. portion of the product of Example 1 was reacted with excess hydrazine in 200 ml. of ethanol for 2 hours, allowing the reaction to heat to reflux temperature. The solids which precipitated upon cooling were separated by filtration and identified as 27 g. of product, m.p. 115°-117°, NMR singlets at 4.48, 7.4, 7.63, 7.97 and 8.73 ppm., and multiplets at 3.05-4.12 and 4.67-5.28 ppm.

Workup

  1. customthe reaction
  2. temperatureto heat
  3. temperatureto reflux temperature
  4. customThe solids which precipitated
  5. temperatureupon cooling
  6. customwere separated by filtration

Sources & evidence

ORD record
ord-b566dea1a1514aaca11ce9b713a2511d
Source dataset
uspto-grants-1981_08
Patent number
US04283403

Reaction notes

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