Methylamine → HCID 12889666, compound

HRID 894327Notes

Reaction equation

HRID 894327 reaction equation
[N:1]([CH2:4][CH:5]1[O:9][N:8]=[C:7]([C:10]2[CH:15]=[CH:14][C:13]([Cl:16])=[CH:12][CH:11]=2)[CH2:6]1)=[C:2]=[S:3].[CH3:17][NH2:18]>C(O)C>[Cl:16][C:13]1[CH:12]=[CH:11][C:10]([C:7]2[CH2:6][CH:5]([CH2:4][NH:1][C:2]([NH:18][CH3:17])=[S:3])[O:9][N:8]=2)=[CH:15][CH:14]=1

Participants

4

Reactant 2

HCID 6329MethylamineHCID 12889638HCID 12889638, compound

Product 1

HCID 12889666HCID 12889666, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

To 3 g. of the product of Example 1 was added 5 ml. of 40 percent methylamine in aqueous ethanol. The mixture was stirred for 1 hour, and was then allowed to stand overnight. The product separated as a precipitate, which was collected and recrystallized from methanol-water, and recrystallized a second time from chloroform to produce 0.8 g. of product, m.p. 131°-133° C.

Workup

  1. waitto stand overnight
  2. customThe product separated as a precipitate
  3. customwhich was collected
  4. customrecrystallized from methanol-water
  5. customrecrystallized a second time from chloroform
  6. customto produce 0.8 g

Sources & evidence

ORD record
ord-7e7f317cea684b4290b2f390c908a203
Source dataset
uspto-grants-1981_08
Patent number
US04283403

Reaction notes

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