Methyl chloroacetate → Sodium 2-methoxy-2-oxoethane-1-sulfonate

HRID 894332Notes

Reaction equation

HRID 894332 reaction equation
Cl[CH2:2][C:3]([O:5][CH3:6])=[O:4].[S:7]([O-:10])([O-:9])=[O:8].[Na+:11].[Na+]>O>[CH3:6][O:5][C:3]([CH2:2][S:7]([O-:10])(=[O:9])=[O:8])=[O:4].[Na+:11]

Participants

4

Reactant 2

HCID 7295Methyl chloroacetateHCID 24437Sodium Sulfite

Product 1

HCID 23705432Sodium 2-methoxy-2-oxoethane-1-sulfonate

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A slurry of 217 g (2 mols) methyl chloroacetate and 252 g (2 mols) sodium sulfite in 500 ml water was stirred and heated under reflux for about 2 hours. The resulting solution was allowed to stand at about 25° C. for 56 hours and then evaporated under reduced pressure to give solid residue. The residue was washed with acetone and dried under vacuum at 80°-90° C. to give crude sodium methoxycarbonylmethylsulfonate salt.

Workup

  1. temperatureheated
  2. temperatureunder reflux for about 2 hours
  3. customevaporated under reduced pressure
  4. customto give solid residue
  5. washThe residue was washed with acetone
  6. customdried under vacuum at 80°-90° C.

Sources & evidence

ORD record
ord-697409e4fbed4761ba661abea6d93501
Source dataset
uspto-grants-1981_08
Patent number
US04283416

Reaction notes

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