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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 894368Generated: October 29, 2026

Ethyl 1-tert-butyl-cyclohexyl-carboxylate → 1-tert-Butylcyclohexane-1-carboxylic acid

https://huagongshe.com/reaction/894368

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 1-tert-butyl-cyclohexyl-carboxylateHCID 20575452—
Reactantpotassium butan-1-olateHCID 178454393—
SolventDimethyl SulfoxideHCID 679—
Product1-tert-Butylcyclohexane-1-carboxylic acidHCID 185606—

Reaction Steps

BuOK in 300 cm3 of anhydrous dimethylsulfoxide and 15.5 g of ethyl 1-tert-butyl-cyclohexyl-carboxylate were heated for 7 hours at 110° C. The mixture was then poured on ice. By acidification with dilute HCl the tert-butyl-cyclohexyl-carboxylic acid was precipitated.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04283420
Source datasetuspto-grants-1981_08
ORD IDord-640f40da0e294733a65df52f9f6ace52
Source noteuspto-grants-1981_08