HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 2-Bromophenylacetyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 2-Bromophenylacetic acid | HCID 87754 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | 2-Bromophenylacetyl chloride | HCID 4138386 | — |
Reaction Steps
For 3 hours, 21 g (0.098 mole) of o-bromophenylacetic acid was refluxed in 100 ml of anhydrous benzene and 23.5 g (0.198 mole) of thionyl chloride. After completion of the reaction, benzene and unreacted thionyl chloride were removed by distillation under reduced pressure so that unreacted thionyl chloride was removed as completely as possible.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04283532 |
| Source dataset | uspto-grants-1981_08 |
| ORD ID | ord-e032945e75a74b5995973d270c9a0711 |
| Source note | uspto-grants-1981_08 |