Hydrochloric Acid → HCID 12616415, compound

HRID 894457Notes

Reaction equation

HRID 894457 reaction equation
O.O.O.O.C([NH:8][C:9]12[CH2:22][C:13]3([NH:23]C(=O)C)[CH2:14][C:15]([NH:18]C(=O)C)([CH2:17][C:11]([NH:27]C(=O)C)([CH2:12]3)[CH2:10]1)[CH2:16]2)(=O)C.[ClH:31]>>[ClH:31].[ClH:31].[ClH:31].[ClH:31].[NH2:8][C:9]12[CH2:16][C:15]3([NH2:18])[CH2:17][C:11]([NH2:27])([CH2:12][C:13]([NH2:23])([CH2:14]3)[CH2:22]1)[CH2:10]2

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 20540997HCID 20540997, compound

Product 1

HCID 12616415HCID 12616415, compoundYield 82%

Procedure

1,3,5,7-Tetraacetamidoadamantane tetrahydrate (2.0 g=4.6 mmoles) was dissolved in 18% hydrochloric acid (30 ml of concentrated hydrochoric acid diluted with 30 ml of water) and the solution was refluxed for three hours. The crystalline product thus obtained was separated from the mixture by filtration, washed with acetone and dried. 1.29 g of product, mp.>360° C., in agreement with that reported by H. Stetter and C. Wulff, Chem. Ber., 93,1366 (1960), corresponding to an 82% yield, were obtained. Analysis. calculated for C10H20H4 .4HCl: C, 35.11; H, 7.07; N, 16.38. Found, C, 34.45; H, 7.17; N, 16.01.

Workup

  1. temperaturethe solution was refluxed for three hours
  2. customThe crystalline product thus obtained
  3. customwas separated from the mixture by filtration
  4. washwashed with acetone
  5. customdried
  6. custom, 93,1366 (1960), corresponding to an 82% yield, were obtained

Sources & evidence

ORD record
ord-e3f3589c024b4fcab0b7df4a48f04704
Source dataset
uspto-grants-1981_08
Patent number
US04284484

Reaction notes

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