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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 894524Generated: October 30, 2026

Imidazole → HCID 20550246, compound

https://huagongshe.com/reaction/894524

Reaction equation

Participants

RoleNameHCIDCharge
ReactantImidazoleHCID 795—
ReactantSodium ethoxideHCID 2723922—
ReactantSodiumHCID 5360545—
Reactant(Bromomethyl)cyclopentaneHCID 12723264—
SolventEthanolHCID 702—
ProductHCID 20550246HCID 20550246—

Reaction Steps

A solution of sodium ethoxide was made by dissolving sodium (2.3 g, 0.1 mole) in absolute ethanol (100 ml). Imidazole (6.8 g, 0.1 mole) was then added. The mixture was heated under reflux and cyclopentylmethylbromide (16.3 g, 0.1 mole) was added dropwise. The reaction mixture was allowed to reflux for a further 16 hours after addition. The mixture was then left to cool.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04284641
Source datasetuspto-grants-1981_08
ORD IDord-8a0567d88b034eec907d7d0dd1a22a41
Source noteuspto-grants-1981_08