HuagongsheHuagongshe Chemistry Print Report · For research reference only
Imidazole → 1-Cycloheptyl-1H-imidazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Imidazole | HCID 795 | — |
| Reactant | Bromocycloheptane | HCID 16992 | — |
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 1-Cycloheptyl-1H-imidazole | HCID 20148467 | — |
Reaction Steps
Cycloheptyl bromide (10.0 g, 0.0565 mole) was added dropwise to a refluxing mixture of imidazole (385 g, 0.0565 mole) and sodium bicarbonate (4.75 g, 0.0565 mole) im methanol (100 ml). After addition was complete the mixture was heated under reflux for a further 24 hours.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04284641 |
| Source dataset | uspto-grants-1981_08 |
| ORD ID | ord-844f90349c9c45a5ae1510e432be5493 |
| Source note | uspto-grants-1981_08 |