Potassium Hydroxide → HCID 12926018, compound

Participants

Reaction Steps

To a solution of 1.09 g. of 6-acetylaminospiro[benzo[b]furan-2(3H),1'-cyclopropane]-3-one in 50 ml. of methanol was added 0.8 g. of potassium hydroxide, and the mixture was refluxed for 0.5 hour. The solvent was evaporated off under reduced pressure. To the residue was added water, and the precipitating crystals were collected by filtration, washed with water and dried. The crystals were recrystallized from methanol to obtain 6-aminospiro[benzo[b]furan-2(3H),1'-cyclopropane]-3-one as colorless prisms melting at 188°-189° C.

Provenance & Evidence