HRID894825

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID76113

Silane, bromotrimethyl-

C3H9BrSi

HCID11355656

未命名化合物

$结构：CO/N=C(\C(=O)N[C@@H]1C(=O)N2C(C(=O)O)=C(COC(=O)NP(=O)(OC)OC)CS[C@H]12)c1ccco1$

HCID88764320

未命名化合物

PRODUCTS

生成物

$结构：CO/N=C(\C(=O)N[C@@H]1C(=O)N2C(C(=O)O)=C(COC(=O)NP(=O)(O)O)CS[C@H]12)c1ccco1$

HCID88760882

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID6344

Dichloromethane

CH2Cl2

2 次

PROCEDURE

实验过程

Bromotrimethylsilane (0.61 g), in dichloromethane (3 ml) was added (at 0° under nitrogen) to a stirred solution of (6R,7R)-3-dimethoxyphosphorylcarbamoyloxymethyl-7-[Z-2-(fur-2-yl)-2-methoxyiminoacetamido]ceph-3-em-4-carboxylic acid (0.53 g) and trimethylsilylurethane (0.965 g) in dry dichloromethane (5 ml). After 1.75 hours no starting cephalosporin remained as indicated by t.l.c.