Diethylaminoethyl chloride → HCID 13205803, Verbindung

HRID 894991Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 894991
[Na].[H-].[Na+].[C:4]1(=[N:16][OH:17])[CH2:15][CH2:14][CH2:13][CH2:12][CH2:11][CH2:10][CH2:9][CH2:8][CH2:7][CH2:6][CH2:5]1.[CH2:18]([N:20]([CH2:24][CH3:25])[CH2:21][CH2:22]Cl)[CH3:19].C(O)(=O)/C=C/C([O-])=O>>[CH2:18]([N:20]([CH2:24][CH2:25][O:17][N:16]=[C:4]1[CH2:15][CH2:14][CH2:13][CH2:12][CH2:11][CH2:10][CH2:9][CH2:8][CH2:7][CH2:6][CH2:5]1)[CH2:21][CH3:22])[CH3:19]

Komponenten

6

Edukt 5

HCID 13364Diethylaminoethyl chlorideHCID 24758Sodium hydrideHCID 136762Cyclododecanone, oximeHCID 5360545SodiumHCID 6183479Fumarate(1-)

Produkt 1

HCID 13205803HCID 13205803, Verbindung

Versuchsvorschrift

The sodium salt is formed in the usual way from 2.4 g. (0.1 moles) of sodium hydride and 19.73 g. (0.1 moles) of cyclododecanone oxime in a toluenic solution and then allowed to react with 14.9 g. (0.11 moles) of 1-diethylamino-2-chloroethane. Otherwise the operations are carried out in accordance with Example 1. Yield: 20 g. (67.56%); b.p. 172°-176° C./0.8 torr. Hydrogen fumarate, m.p.: 112°-114° C.

Aufarbeitung

  1. customto react with 14.9 g

Quellen und Nachweise

ORD-Eintrag
ord-f89de6bdb16a4847969e19ea312840e6
Quelldatensatz
uspto-grants-1981_08
Patentnummer
US04285942

Notizen zur Reaktion

Wird geladen…