HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethylaminoethyl chloride → 1-(Diethylamino-ethoxyimino)cyclododecane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethylaminoethyl chloride | HCID 13364 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | Cyclododecanone, oxime | HCID 136762 | — |
| Reactant | Sodium | HCID 5360545 | — |
| Reactant | Fumarate(1-) | HCID 6183479 | — |
| Product | 1-(Diethylamino-ethoxyimino)cyclododecane | HCID 13205803 | — |
Reaction Steps
The sodium salt is formed in the usual way from 2.4 g. (0.1 moles) of sodium hydride and 19.73 g. (0.1 moles) of cyclododecanone oxime in a toluenic solution and then allowed to react with 14.9 g. (0.11 moles) of 1-diethylamino-2-chloroethane. Otherwise the operations are carried out in accordance with Example 1. Yield: 20 g. (67.56%); b.p. 172°-176° C./0.8 torr. Hydrogen fumarate, m.p.: 112°-114° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04285942 |
| Source dataset | uspto-grants-1981_08 |
| ORD ID | ord-f89de6bdb16a4847969e19ea312840e6 |
| Source note | uspto-grants-1981_08 |