Ethylenediamine → HCID 178433680, compound

HRID 895025Notes

Reaction equation

[C:1]([NH:3][C:4](=[N:7][CH2:8][CH2:9][S:10][CH2:11][C:12]1[N:13]=[CH:14][NH:15][C:16]=1[CH3:17])SC)#[N:2].[NH2:18][CH2:19][CH2:20][NH2:21]>>[C:1]([NH:3][C:4]([NH:18][CH2:19][CH2:20][NH2:21])=[N:7][CH2:8][CH2:9][S:10][CH2:11][C:12]1[N:13]=[CH:14][NH:15][C:16]=1[CH3:17])#[N:2]

Participants

Reactant 2

HCID 3301Ethylenediamine

HCID 1036301-Cyano-2-methyl-3-(2-(((5-methyl-1H-imidazol-4-yl)methyl)thio)ethyl)isothiourea

Product 1

HCID 178433680HCID 178433680, compound

Procedure

Reaction of N-cyano-N'-[2-((5-methyl-4-imidazolyl)-methylthio)ethyl]-S-methylisothiourea with excess 1,2-diaminoethane at room temperature gave N-cyano-N'-(2-aminoethyl)-N"-[2-((5-methyl-4-imidazolyl)methylthio)ethyl]guanidine, m.p. 164°-167°.

Sources & evidence

ORD record: ord-fedc8bc493614fc9b33b8380fdd55354
Source dataset: uspto-grants-1981_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04285952

Reaction notes

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