Ethanolamine → HCID 12193781, compound

HRID 895313Notes

Reaction equation

[C:1]([O:5][CH3:6])(=[O:4])[CH:2]=[CH2:3].[NH2:7][CH2:8][CH2:9][OH:10]>>[OH:10][CH2:9][CH2:8][N:7]([CH2:3][CH2:2][C:1]([O:5][CH3:6])=[O:4])[CH2:3][CH2:2][C:1]([O:5][CH3:6])=[O:4]

Participants

Reactant 2

HCID 700Ethanolamine

HCID 7294Methyl Acrylate

Product 1

HCID 12193781HCID 12193781, compoundYield 100.6%

Procedure

At 20 to 30° C., 15.5 g of methyl acrylate was added to 5.00 g of 2-aminoethanol. The resulting mixture was allowed to stand for 20 hours, followed by concentration under reduced pressure, whereby 19.2 g of N-(2-hydroxyethyl)bis[2-(methoxycarbonyl)ethyl]amine was obtained (at a quantitative yield)

Workup

concentrationfollowed by concentration under reduced pressure

Sources & evidence

ORD record: ord-15ebc2857f5a43a8973dd8be9a8ccf56
Source dataset: uspto-grants-2005_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06916593B2

Reaction notes

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