Piperidine → N-(6-chloro-2-phenylpyrimidin-4-yl)-2-piperidin-1-ylacetamide

Beteiligte Stoffe

Reaktionsschritte

2-Bromo-N-(6-chloro-2-phenylpyrimidin-4-yl)acetamide (28 mg) was dissolved in acetonitrile (2 ml) and piperidine added (23 μl in 500 ul acetonitrile). The mixture was left to stir for 1.5 hr after which time the solvent was removed in vacuo. Purification using a short silica plug, eluting with a mixture of ethyl acetate and petroleum ether (1:1 v/v) furnished the title compound (25 mg).

Herkunft & Nachweise