HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 895626Generated: October 31, 2026
4-Phenyl-1,2,3,6-tetrahydropyridine hydrochloride → 4-Phenylpiperidinium chloride
https://huagongshe.com/reaction/895626
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 4-Phenyl-1,2,3,6-tetrahydropyridine hydrochloride | HCID 2723860 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 4-Phenylpiperidinium chloride | HCID 82509 | 99% |
Reaction Steps
1,2,3,6-Tetrahydro-4-phenylpyridine hydrochloride (70 mg) was dissolved in methanol (1.4 ml), added with 10% palladium/carbon (35 mg) and stirred at 45° C. for 5 hours under hydrogen gas atmosphere. After insoluble matters were removed by filtration, the solvent was evaporated under reduced pressure to obtain 70.0 mg of the title compound. Yield: 99%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06916822B2 |
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| Source dataset | uspto-grants-2005_07 |
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| ORD ID | ord-07a5ec0616424cb3a181b522793b23b8 |
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| Source note | uspto-grants-2005_07 |
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