4-N-ethylpyridine-3,4-diamine → 1-ethyl-2-(2-thiazol-2-yl-imidazol-1-ylmethyl)-1H-imidazo[4,5-c]pyridine

Participants

Role	Name	HCID	Charge
Reactant	4-N-ethylpyridine-3,4-diamine	HCID 12036392	—
Reactant	(2-Thiazol-2-yl-imidazol-1-yl)-acetic acid methyl ester	HCID 68495873	—
Product	1-ethyl-2-(2-thiazol-2-yl-imidazol-1-ylmethyl)-1H-imidazo[4,5-c]pyridine	HCID 22380006	—

Reaction Steps

The title compound is prepared from N4-ethyl-pyridine-3,4-diamine and (2-thiazol-2-yl-imidazol-1-yl)-acetic acid methyl ester following the procedure given in Example 8. 1H NMR (CDCl3) δ 9.08 (s, 1 H), 8.43 (d, 1 H), 7.85 (d, 1 H), 7.38 (d, 1 H), 7.38-7.26 (m, 1 H), 7.17 (s, 1 H), 7.14 (s, 1 H), 6.35 (s, 2 H), 4.25 (q, 2 H), 1.11 (t, 3 H). Electrospray MS: m/z 311 [M+1]

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US06916827B2
Source dataset	uspto-grants-2005_07
ORD ID	ord-e193dd037c34465a9939b51b3c07234f
Source note	uspto-grants-2005_07