2-(2-Methyl-2-nitropropyl)naphthalene → alpha,alpha-Dimethyl-2-naphthaleneethanamine

HRID 895870Notes

Reaction equation

HRID 895870 reaction equation
[CH3:1][C:2]([N+:15]([O-])=O)([CH3:14])[CH2:3][C:4]1[CH:13]=[CH:12][C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:5]=1>[Ni].C(O)C>[CH3:14][C:2]([NH2:15])([CH3:1])[CH2:3][C:4]1[CH:13]=[CH:12][C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[CH:5]=1

Participants

4

Reactant 1

HCID 99646182-(2-Methyl-2-nitropropyl)naphthalene

Product 1

HCID 15369616alpha,alpha-Dimethyl-2-naphthaleneethanamine

Reagents, catalysts & solvents 2

HCID 935NickelCatalystHCID 702EthanolSolvent

Procedure

Raney nickel W2 (200 mg) was suspended in ethanol (10 ml), to the suspension was added 2-(2-methyl-2-nitropropyl)naphthalene (134 mg) obtained in Step 5, and hydrogenation was performed at a pressure of 3.5 atom for 12 hr.

Sources & evidence

ORD record
ord-850220ed51ca439d8c25e5a01a31a0ff
Source dataset
uspto-grants-2005_07
Patent number
US06916956B2

Reaction notes

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