HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → 6,8-Dibromoimidazo[1,2-a]pyrazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | 2-Amino-3,5-dibromopyrazine | HCID 620004 | — |
| Product | 6,8-Dibromoimidazo[1,2-a]pyrazine | HCID 15025843 | — |
Reaction Steps
A solution of 1.00 equivalents (eq.) of 3,5-dibromo-2-aminopyrazine 1 in ethanol is treated with 2.00 eq. of α-bromoaldehyde 2 at room temperature (RT) and heated for 48 hours (hr). The solvent is removed under reduced pressure and the residue is triturated with diethyl ether and filtered to give the HBr salt 3.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06919340B2 |
| Source dataset | uspto-grants-2005_07 |
| ORD ID | ord-0787d25f1e61467194acbab7800f10ec |
| Source note | uspto-grants-2005_07 |