HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonium Chloride → 6-amino-3-ethyl-4-fluoro-1,3-benzoxazol-2(3H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonium Chloride | HCID 25517 | — |
| Reactant | HCID 45095618 | HCID 45095618 | — |
| Catalyst | Iron | HCID 23925 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Water | HCID 962 | — |
| Product | 6-amino-3-ethyl-4-fluoro-1,3-benzoxazol-2(3H)-one | HCID 68490571 | — |
Reaction Steps
Prepared from 3-ethyl-4-fluoro-6-nitro-1,3-benzoxazol-2(3H)-one (Step 1, 1.05 g, 4.90 mmol), ammonium chloride (2.62 g, 49 mmol) and iron powder (1.09 g, 19.6 mmol) in ethanol (30 ml) and water (15 ml) according to the method of EXAMPLE 86, Step 7 (0.95 g, 99%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06919329B2 |
| Source dataset | uspto-grants-2005_07 |
| ORD ID | ord-749f4ec2a8264e54816f1e2671b08f23 |
| Source note | uspto-grants-2005_07 |