HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(4-Fluorophenyl)-3-hydroxy-3-pyridin-4-yl-propionic acid methyl ester → 2-(4-Fluorophenyl)-3-(2-methylsulfanyl-pyrimidin-4-yl)-3-oxo-propionic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(4-Fluorophenyl)-3-hydroxy-3-pyridin-4-yl-propionic acid methyl ester | HCID 12150536 | — |
| Reactant | 2-(4-Fluorophenyl)-3-(2-methylsulfanyl-pyrimidin-4-yl)-3-hydroxypropionic acid methyl ester | HCID 12991402 | — |
| Product | 2-(4-Fluorophenyl)-3-(2-methylsulfanyl-pyrimidin-4-yl)-3-oxo-propionic acid methyl ester | HCID 12991403 | — |
Reaction Steps
Using the procedure from Example 1b set forth above, substitute 2-(4-fluorophenyl)-3-hydroxy-3-(2-methylsulfanyl-pyrimidin-4-yl)-propionic acid methyl ester for 2-(4-fluorophenyl)-3-hydroxy-3-pyridin-4-yl-propionic acid methyl ester to produce the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06919346B2 |
| Source dataset | uspto-grants-2005_07 |
| ORD ID | ord-350b1ad44b624ecb82efcddfc8c07708 |
| Source note | uspto-grants-2005_07 |