反应详情

4-benzyloxy-3-methoxybenzaldehyde (4.84 g, 20 mmol) in acetic acid (25 ml) and sodium acetate (3.3 g, 40 mmol) was reacted with hydroxylamine hydrochloride (2.8 g, 40 mmol) at reflux for 6 hours. The mixture was cooled, diluted with water, extracted with methylene chloride, dried over MgSO4, concentrated to give title compound (4.8 g, 100%).

1. temperatureat reflux for 6 hours
2. temperatureThe mixture was cooled
3. extractionextracted with methylene chloride
4. dry with materialdried over MgSO4
5. concentrationconcentrated