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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 896266Generated: October 30, 2026

Sodium → HCID 22349636, compound

https://huagongshe.com/reaction/896266

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodiumHCID 5360545—
ReactantHCID 86589729HCID 86589729—
SolventEthanolHCID 702—
ProductHCID 22349636HCID 2234963682.6%

Reaction Steps

Methyl(2-tert-butoxycarbonylamino-1,3-thiazole-5-yl)(oxo)acetate (1.14 g, 4 mmol) in ethanol (10 ml) was treated with sodium hydroxyde (2N, 4 ml, 8 mmol) for 3M minutes at room temperature. Ethanol was removed, the aqueous solution was acidified (pH 3). The solid was recovered, dried to give title product (900 mg, 82%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06919338B2
Source datasetuspto-grants-2005_07
ORD IDord-84db59fea1e7438b8bf3b8cdca3f5b70
Source noteuspto-grants-2005_07