HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(2,3-Dihydroimidazo[2,1-b][1,3]thiazol-6-yl)methanamine → 6-({[(8-Hydroxy-1,6-naphthyridin-7-yl)carbonyl]amino}methyl)-2,3-dihydroimidazo[2,1-b][1,3]thiazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(2,3-Dihydroimidazo[2,1-b][1,3]thiazol-6-yl)methanamine | HCID 7061891 | — |
| Reactant | Benzimidazol-2-ylmethylamine, oxamethane, chloride, chloride | HCID 43835646 | — |
| Reactant | HCID 178420910 | HCID 178420910 | — |
| Product | 6-({[(8-Hydroxy-1,6-naphthyridin-7-yl)carbonyl]amino}methyl)-2,3-dihydroimidazo[2,1-b][1,3]thiazole | HCID 9858580 | — |
Reaction Steps
The title compound was prepared as the imidazothiazol-4-ium trifluoroacetate salt using the procedure described in Example 1, Step 4 replacing 2-(ammoniomethyl)-1H-benzimidazol-1-ium dichloride hydrate with 1-(2,3-dihydroimidazo[2,1-b][1,3]thiazol-6-yl)methanamine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06919351B2 |
| Source dataset | uspto-grants-2005_07 |
| ORD ID | ord-1416935972c34105b615310d48bed2d3 |
| Source note | uspto-grants-2005_07 |