HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclopropylamine → N-Cyclopropyl-3-nitropyridin-4-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclopropylamine | HCID 69828 | — |
| Reactant | 4-Methoxy-3-nitropyridine | HCID 355832 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | N-Cyclopropyl-3-nitropyridin-4-amine | HCID 22349359 | — |
Reaction Steps
A solution of 4-methoxy-3-nitropyridine (7.71 g, 50 mmol) and cyclopropylamine (7.14 g, 125 mmol) in EtOH (20 mL) was heated at 80° C. in a sealed tube for 2 h. The solvent was evaporated to give cyclopropyl-(3-nitro-pyridin-4-yl)-amine as a yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06919331B2 |
| Source dataset | uspto-grants-2005_07 |
| ORD ID | ord-942d2294fd7f41c6ae865d9f689aecfc |
| Source note | uspto-grants-2005_07 |