Diisopropyl Ether → HCID 10291485, compound

HRID 896443Notes

Reaction equation

HRID 896443 reaction equation
[OH:1][C:2]1[CH:3]=[CH:4][C:5]2[N:9]=[C:8]([C:10]([OH:12])=O)[NH:7][C:6]=2[CH:13]=1.C[CH:15]([CH:22]1[CH2:27][CH2:26][NH:25][CH2:24][CH2:23]1)[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1.[CH:28](OC(C)C)(C)C>>[OH:1][C:2]1[CH:3]=[CH:4][C:5]2[N:9]=[C:8]([C:10]([N:25]3[CH2:24][CH2:23][CH:22]([CH2:15][C:16]4[CH:17]=[CH:18][C:19]([CH3:28])=[CH:20][CH:21]=4)[CH2:27][CH2:26]3)=[O:12])[NH:7][C:6]=2[CH:13]=1

Participants

4

Reactant 3

HCID 7914Diisopropyl EtherHCID 21403015791726-25-5HCID 223501686-Hydroxy-1H-benzimidazole-2-carboxylic acid

Product 1

HCID 10291485HCID 10291485, compound

Procedure

The title compound is prepared from 6-hydroxy-1H-benzoimidazole-2-carboxylic acid [Example elözö d] and 4-(-methylbenzyl)piperidine [J. Org. Chem., 64, 3763 (1999)] according to the method described in Example 25. Mp.: 93° C. (diisopropyl ether).

Sources & evidence

ORD record
ord-73e45b30a2de4d5da93828b290ae6aea
Source dataset
uspto-grants-2005_07
Patent number
US06919355B2

Reaction notes

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