HCID 22351066, compound → HCID 22351084, compound

Participants

Reaction Steps

The compound obtained in Example 37 is dissolved in a methanol/THF/dioxane solvent mixture and then a catalytic amount of palladium-on-carbon is added and the reaction is stirred at ambient temperature under a hydrogen atmosphere. The palladium-on-carbon is then filtered off and the solvents are removed by evaporation under reduced pressure. The resulting residue is taken up in isopropyl ether and stirred magnetically. The resulting precipitate is filtered off and recrystallised from methanol.

Provenance & Evidence