Diazomethane → Methyl 2-(4-(methylthio)phenyl)acetate

HRID 896658Notes

Reaction equation

HRID 896658 reaction equation
[CH3:1][S:2][C:3]1[CH:8]=[CH:7][C:6]([CH2:9][C:10]([OH:12])=[O:11])=[CH:5][CH:4]=1.[N+](=[CH2:15])=[N-]>>[CH3:15][O:11][C:10](=[O:12])[CH2:9][C:6]1[CH:5]=[CH:4][C:3]([S:2][CH3:1])=[CH:8][CH:7]=1

Participants

3

Reactant 2

HCID 9550DiazomethaneHCID 49839124-(Methylthio)phenylacetic acid

Product 1

HCID 12067662Methyl 2-(4-(methylthio)phenyl)acetate

Procedure

(4-Methylsulfanyl-phenyl)-acetic acid was treated with an etheral solution of diazomethane until completion of esterification. The solvent was evaporated, the residue triturated in hexane/ether, and filtered to afford the title compound as a white solid.

Workup

  1. customThe solvent was evaporated
  2. customthe residue triturated in hexane/ether
  3. filtrationfiltered

Sources & evidence

ORD record
ord-7d7dfc862ffb4d99af292e0bc0a387fb
Source dataset
uspto-grants-2005_07
Patent number
US06919353B2

Reaction notes

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