HRID896935

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID79341

Piperidin-4-ol

C5H11NO

结构：CN(C(=O)OC(C)(C)C)[C@H](Cc1ccccc1)C(=O)O

HCID7015127

未命名化合物

结构：CN(C(=O)OC(C)(C)C)[C@H](Cc1ccc2ccccc2c1)C(=O)O

HCID10065151

未命名化合物

HCID10729698

未命名化合物

PRODUCTS

生成物

结构：CN(C(=O)/C=C/CC1(N)CCC1)[C@H](Cc1ccc2ccccc2c1)C(=O)N(C)[C@H](Cc1ccccc1)C(=O)N1CCC(O)CC1

HCID9895138

未命名化合物

PROCEDURE

实验过程

This compound was prepared as in example 1 but using 4-hydroxypiperidine, (2R)-2-(N-tert-butoxycarbonyl-N-methylamino)-3-phenylpropionic acid and (2R)-2-(N-tert-butoxycarbonyl-N-methylamino)-3-(2-naphthyl)propionic acid and (2E)-4-(1-(tert-butoxycarbonylamino)cyclobutyl)but-2-enoic acid.

WORKUP

后处理

customThis compound was prepared as in example 1

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-e38168170865494da227c1f91bd0acf3
来源数据集: uspto-grants-2005_07
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06919315B1
来源说明: uspto-grants-2005_07

反应 SMILES

[OH:1][CH:2]1[CH2:7][CH2:6][NH:5][CH2:4][CH2:3]1.C(OC([N:15]([C@H:17]([CH2:21][C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1)[C:18]([OH:20])=O)[CH3:16])=O)(C)(C)C.C(O[C:33]([N:35]([C@H:37]([CH2:41][C:42]1[CH:51]=[CH:50][C:49]2[C:44](=[CH:45][CH:46]=[CH:47][CH:48]=2)[CH:43]=1)[C:38]([OH:40])=O)[CH3:36])=[O:34])(C)(C)C.C(OC([NH:59][C:60]1([CH2:64]/[CH:65]=[CH:66]/C(O)=O)[CH2:63][CH2:62][CH2:61]1)=O)(C)(C)C>>[CH2:21]([C@@H:17]([N:15]([CH3:16])[C:38]([C@H:37]([N:35]([CH3:36])[C:33](=[O:34])/[CH:66]=[CH:65]/[CH2:64][C:60]1([NH2:59])[CH2:63][CH2:62][CH2:61]1)[CH2:41][C:42]1[CH:51]=[CH:50][C:49]2[C:44](=[CH:45][CH:46]=[CH:47][CH:48]=2)[CH:43]=1)=[O:40])[C:18]([N:5]1[CH2:6][CH2:7][CH:2]([OH:1])[CH2:3][CH2:4]1)=[O:20])[C:22]1[CH:23]=[CH:24][CH:25]=[CH:26][CH:27]=1