Isopropanol → 5-iodo-6-methyl-N-(3-(trifluoromethyl)phenyl)isoquinolin-1-amine
Reaction equation
[CH:25]([OH:26])([CH3:27])[CH3:28].[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6]2[c:7]([I:13])[c:8]([CH3:12])[cH:9][cH:10][c:11]12.[F:14][C:15]([c:16]1[cH:17][c:18]([NH2:19])[cH:20][cH:21][cH:22]1)([F:23])[F:24]>>[c:2]1([NH:19][c:18]2[cH:17][c:16]([C:15]([F:14])([F:23])[F:24])[cH:22][cH:21][cH:20]2)[n:3][cH:4][cH:5][c:6]2[c:7]([I:13])[c:8]([CH3:12])[cH:9][cH:10][c:11]12Participants
4
Sources & evidence
- ORD record
- ord-cd12c99570024971bc3e438219236553
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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