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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 897377Generated: October 30, 2026

Sodium Hydroxide → HCID 68897208, compound

https://huagongshe.com/reaction/897377

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
ReactantHCID 16728075HCID 16728075—
SolventAcetonitrileHCID 6342—
ProductHCID 68897208HCID 68897208—

Reaction Steps

To a suspension of N-{2-[(dimethylamino)sulfonyl]-4-fluorobenzyl}-5-(1,1-dioxido-1,2-thiazinan-2-yl)-8-hydroxy-1,6-naphthyridine-7-carboxamide (147 mg, 0.27 mmol) in acetonitrile (1 mL) was added 1N sodium hydroxide (287 μL, 0.29 mmol). After the solution became homogeneous, the sample was concentrated in vacuo to afford the title compound as a yellow solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06921759B2
Source datasetuspto-grants-2005_07
ORD IDord-84949087ba9a4ab6bd211db603cb757b
Source noteuspto-grants-2005_07